An international study led by Imperial College London and supported by the Medicines and Healthcare products Regulatory Agency (MHRA) has mapped the spread of vaccine‑derived poliovirus type 2 (cVDPV2). The analysis of 3,893 cases from 74 outbreaks in 39 countries between 2016 and 2023 found that the virus moves at a median speed of 2.3 kilometres per day, primarily between neighbouring countries. Most outbreaks were small, with a median of 4.5 cases, but some affected up to 14 countries. Borders were shown to slow transmission by up to 38 %, likely due to higher immunity from vaccination campaigns. The research also shows that historic wild‑type poliovirus spread patterns mirror current cVDPV2 routes. Findings suggest that early preventive vaccination in low‑immunity neighbours could improve outbreak response.
© Crown copyright, 2024, GOV.UK.
Summary adapted from content licensed under the Open Government Licence v3.0.
For details, see https://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/.
Original source: https://www.gov.uk/
https://www.gov.uk/government/news/new-mhra-supported-research-reveals-patterns-of-vaccine-derived-poliovirus-spread-and-implications-for-global-eradication-efforts
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